Ambrafuran (AmbroxTM) Synthesis from Natural Plant Product Precursors
نویسندگان
چکیده
منابع مشابه
Natural Product Synthesis
The Lycopodium alkaloids are a family of structurally complex natural products, which have provoked long-term interests in their total syntheses because of their unique and fascinating architectures and potential biological activities. In particular, fawcettimine-type Lycopodium alkaloids, such as fawcettimine (1) and fawcettidine (2) (Scheme 1), have attracted broad attention from the syntheti...
متن کامل“ Metathesis in Natural Product Synthesis ”
Institute of Organic Chemistry, Romanian Academy, 202B Spl. Independentei, PO Box 35-108, 060023 Bucharest, Romania; E-mail: *[email protected]; **[email protected] “Metathesis in Natural Product Synthesis” subtitled ‘Strategies, Substrates and Catalysts’ benefits from a foreword by Robert H. Grubbs, joint recipient of the 2005 Nobel Prize in Chemistry for his work on the development of the...
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A ctivate. Couple. Deprotect. Repeat. So goes the cycle of peptide synthesis, whereby amino acids are iteratively connected to produce oligopeptides. However, only peptides that are fewer than approximately 50 residues can typically be accessed through solid-phase peptide synthesis. Thus, a defining moment in the field of peptide synthesis came about with the advent of native chemical ligation ...
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An important aim in biology research is the elucidation of the role of proteins in complex, dynamic biological systems through the selective perturbation of their function. In contrast to genetic perturbations, chemical perturbations of protein function are conditional, acute, easily tuneable and reversible. [1] Furthermore, drug development still largely depends on the availability of bioactiv...
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ژورنال
عنوان ژورنال: Molecules
سال: 2020
ISSN: 1420-3049
DOI: 10.3390/molecules25173851